The efficient synthesis of methyl 2-benzyloxycarbonylamino-(1S, 2R)-cyclobutane-1- carboxylate starting from 2-methoxycarbonyl-(1R, 2S)-cyclobutane-1-carboxylic acid is described. This β-amino acid derivative is antipodal with respect to the (1R, 2S)-compound that was previously synthesized in our laboratory from the same chiral hemi ester. In turn, these enantiomeric β-amino acids have been self-condensed and coupled with one ...
