The Journal of organic chemistry

Click chemistry to construct fluorescent oligonucleotides for DNA sequencing

TS Seo, Z Li, H Ruparel, J Ju

文献索引：Journal of Organic Chemistry, , vol. 68, # 2 p. 609 - 612

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被引用次数: 275

摘要

... The Journal of Organic Chemistry. ... gel TLC plate (1:9 MeOH/CHCl 3 ) to give 8.0 mg (85%) of alkynyl FAM (R f = 0.45) as a red oil: 1 H NMR (methanol-d 4 ) δ 8.01 (s, 2H), 7.60 (s, 1H), 6.94 (d, 2H, J = 9.1 Hz), 6.58−6.53 (m, 4H), 4.05 (d, 2H, J = 2.4 Hz), 2.50 (t, 1H, J = 2.2 Hz ...