An optimized RAD51 inhibitor that disrupts homologous recombination without requiring Michael acceptor reactivity

B Budke, JH Kalin, M Pawlowski…

文献索引：Journal of Medicinal Chemistry, , vol. 56, # 1 p. 254 - 263

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被引用次数: 34

摘要

... Journal of Medicinal ... University of Chicago, 5758 S. Maryland Avenue, Chicago, Illinois 60637, United States. ‡ Department of Medicinal Chemistry and Pharmacognosy ... To overcome this problem, we generated chemical analogues that maintain binding to RAD51 but lack the ...