Synthesis of novel 5-amino-1-aroylpyrazoles

…, J Portilla, R Abonía, B Insuasty, M Nogueras, J Cobo

文献索引：Quiroga, Jairo; Portilla, Jaime; Abonia, Rodrigo; Insuasty, Braulio; Nogueras, Manuel; Cobo, Justo Tetrahedron Letters, 2008 , vol. 49, # 41 p. 5943 - 5945

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被引用次数: 12

摘要

A series of 5-amino-1-aroylpyrazoles 3 are synthesized directly by the reaction of β- aminocrotononitrile 1 with some structures containing the hydrazine moiety (X-NHNH2) 2 by refluxing ethanol in presence of sodium acetate. When semicarbazide 3i was used (X= CONH2), the reaction afforded the unexpected 7-aminopyrazolo [1, 5-a] pyrimidine 4.