SAR studies of epoxycurcuphenol derivatives on leukemia CT-CD4 cells

…, M Macías, JMG Molinillo, A Muñoz-Suano…

文献索引：Galindo, Jose L.G.; MacIas, Mariola; Molinillo, Jose M.G.; Munoz-Suano, Alba; Torres, Ascension; Varela, Rosa M.; Garcia-Cozar, Francisco; MacIas, Francisco A. Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 22 p. 6662 - 6668

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被引用次数: 1

摘要

Bioactive natural products are a potential source of new pharmaceuticals since they offer new modes of action and more specific activities. The use of derivatization also enables the optimal structure for their biological activity to be determined. In this study several epoxycurcuphenol derivatives were synthesized. The substitution pattern on the aromatic and oxirane rings was varied along with that at the benzylic position and the length of the ...