Furanyl-1, 3-thiazol-2-yl and benzoxazol-5-yl acetic acid derivatives: novel classes of heparanase inhibitor

SM Courtney, PA Hay, RT Buck, CS Colville…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 9 p. 2295 - 2299

全文：HTML全文

被引用次数: 23

摘要

... Bioorganic & Medicinal Chemistry Letters. ... Although a relatively weak starting point for a medicinal chemistry programme, the paucity of reported heparanase inhibitors, coupled with its scope for structural changes, encouraged us to explore the SAR of this scaffold. ...