Discovery of novel and potent aryl diamines as leukotriene A 4 hydrolase inhibitors

SK Khim, J Bauman, J Evans, B Freeman…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 14 p. 3895 - 3898

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被引用次数: 9

摘要

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... 18 In this letter, we describe the transition of N-alkyl glycine amide 1 to the aryl diamine template of potent, selective, and orally available inhibitors of LTA 4 -h. ...