Synthesis of pyrroloquinolines as indole analogues of flavonols

DSC Black, N Kumar, PSR Mitchell

文献索引：Black, David St.C.; Kumar, Naresh; Wong, Laurence C. H. Australian Journal of Chemistry, 1986 , vol. 39, p. 15 - 20

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被引用次数: 26

摘要

7-Acetyl-4, 6-dimethoxy-3-phenylindole 10 was converted into a range of 7-indolyl chalcones 13 by reaction with aryl aldehydes under basic conditions. Oxidation of the chalcones 13 with alkaline hydrogen peroxide gave the isolable epoxides 14, which were

~90%

119-53-9

2-羟基-2-苯基苯乙酮

~52%

~49%

~95%

Both 5-arylidene-2-thioxodihydropyrimidine-4, 6 (1H, 5H)-dio...

[Voss, Matthew E.; Carter, Percy H.; Tebben, Andrew J.; Scherle, Peggy A.; Brown, Gregory D.; Thompson, Lorin A.; Xu, Meizhong; Lo, Yvonne C.; Yang, Gengjie; Liu, Rui-Qin; Strzemienski, Paul; Everlof, J. Gerry; Trzaskos, James M.; Decicco, Carl P. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 533 - 538]