The interaction of perfluoroalkylacetones of formula RFCH2COCH3 (RF= n-C3F7, n-C4F9, n- C6F13, n-C8F17) with ammonia and primary and secondary amines has been studied. In all cases, nucleophilic reagents initially dehydrofluorinate the starting ketone, and then substitution of the vinyl fluorine atom by a nucleophile occurs to give aza analogues of β- dicarbonyl compounds RFC (NR2)= CH-C (O) CH3; their hydrolysis yields the ...
