Tagged phosphine reagents to assist reaction work-up by phase-switched scavenging using a modular flow reactor
…, IR Baxendale, GK Tranmer, M Baumann…
文献索引：Smith, Christopher D.; Baxendale, Ian R.; Tranmer, Geoffrey K.; Baumann, Marcus; Smith, Stephen C.; Lewthwaite, Russell A.; Ley, Steven V. Organic and Biomolecular Chemistry, 2007 , vol. 5, # 10 p. 1562 - 1568
The use of three orthogonally tagged phosphine reagents to assist chemical work-up via phase-switch scavenging in conjunction with a modular flow reactor is described. These techniques (acidic, basic and Click chemistry) are used to prepare various amides and tri- substituted guanidines from in situ generated iminophosphoranes.
