Some comments on an allegedly “facile synthesis of nojirimycin”
…, NG Ramsden, NM Carpenter, S Peturssona, RT Aplin
文献索引：Fleet, George W. J.; Ramsden, Nigel G.; Carpenter, Neil M.; Peturssona, Sigthor; Aplin, Robin T. Tetrahedron Letters, 1990 , vol. 31, # 3 p. 405 - 408
Difficulties in repeating a short synthesis of nojirimycin from 2, 3, 4, 6-tetra-0-benzyl-D- glucono-&lactone are reported. f# ecently, a short synthesis of nojirimycln (1) from tetra-0- benzyl-glucono-6-lactonel contained only two simple-but remarkable-steps. First, the reaction of the lactone (2) with amines under mild conditions gave the corresponding lactams in which nitrogen had replaced oxygen at C-5 with retention of configuration; for ...
