N-(2-Benzoylphenyl)-L-tyrosine PPARγ agonists. 2. Structure-activity relationship and optimization of the phenyl alkyl ether moiety

JL Collins, SG Blanchard, GE Boswell…

文献索引：Journal of Medicinal Chemistry, , vol. 41, # 25 p. 5037 - 5054

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被引用次数: 127

摘要

... Journal of Medicinal ... We now report the expanded structure−activity relationship around the phenyl alkyl ether moiety by pursuing both a classical medicinal chemistry approach and a solid-phase chemistry approach for analogue synthesis. ... Chemistry. Solution-Phase Chemistry. ...