Novel substituted pyridinyl imidazoles as potent anticytokine agents with low activity against hepatic cytochrome P450 enzymes

SA Laufer, GK Wagner…

文献索引：Adger, Brian M.; Ayrey, Peter; Bannister, Robin; Forth, Michael A.; Hajikarimian, Yousef; et al. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2791 - 2796

全文：HTML全文

被引用次数: 102

摘要

... Journal of Medicinal ... 2003, 46 (15), pp 3230–3244. DOI: 10.1021/jm030766k. Publication Date (Web): June 24, 2003. Copyright © 2003 American Chemical Society. ... Placement of a 1-phenylethyl (7e, p38: IC 50 0.38 μM) or acetyl substituent at the exocyclic nitrogen of several 2 ...