Conjugate addition of alkyl groups to α, β-unsaturated sulfoxides via Michael addition of nitroparaffins and subsequent denitration with tributyltin hydride
Abstract Michael addition of nitroparaffins to α, β-unsaturated sulfoxides is well effected in the presence of DBU. The nitro group in the adduct is replaced by hydrogen with Bu 3 SnH without influence to the sulfinyl function. The overall reations provide an efficient method for the conjugate addition of alkyl groups to α, β-unsaturated sulfoxides.
