Acta Pol. Pharm. Drug Res

Synthesis and in vitro antimicrobial activity of novel 2-(3-oxo-1, 3-diarylpropylthio) acetic acid derivatives

H Gezegen, İSA Karaman, M Ceylan…

文献索引：Gezegen, Hayreddin; Karaman, Isa; Ceylan, Mustafa; Dilmac, Merve Acta Poloniae Pharmaceutica - Drug Research, 2012 , vol. 69, # 5 p. 893 - 900

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被引用次数: 4

摘要

Abstract: A series of novel 2-(3-oxo-1, 3-diarylpropylthio) acetic acid derivatives (3añl) were prepared by base catalyzed addition of thioglycolic acid to chalcones (1añl). The antibacterial activities of synthesized compounds were screened against human pathogenic microorganisms by employing the disk-diffusion technique. For the active compounds, also minimum inhibitory concentrations (MICs) were determined. Keywords: thioglycolic acid, ...