RSC Advances

Iron-catalyzed aryl-aryl cross coupling route for the synthesis of 1-(2-amino)-phenyl) dibenzo [b, d] furan-2-ol derivatives and their biological evaluation

…, G Koyyada, S Prabusreenivasan, V Kumar, P Sujitha…

文献索引：Chiranjeevi, Barreddi; Koyyada, Ganesh; Prabusreenivasan; Kumar, Vanaja; Sujitha, Pombala; Kumar, C. Ganesh; Sridhar; Shaik, Saida; Chandrasekharam, Malapaka RSC Advances, 2013 , vol. 3, # 37 p. 16475 - 16485

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被引用次数: 6

摘要

Naturally occurring dibenzofuran motifs represent promising lead structures for the development of novel antimycobacterial agents. Prompted by our recent development of cross dehydrogenative coupling using iron catalysis, we extended our strategy to synthesize 14 novel anilinodibenzofuranols and they were explored for anti-tubercular and cytotoxic activities. Consistent with our hypothesis, DBF-3, 14 and 16 exhibited promising activity ...