Pd (II)-catalyzed ortho arylation of 6-arylpurines with aryl iodides via purine-directed C− H activation: A new strategy for modification of 6-arylpurine derivatives
Purine is utilized as a new directing group for the Pd-catalyzed monoarylation of 6- arylpurines with simple aryl iodides via C− H bond activation in good yields, providing a complementary tool for the modification of 6-arylpurines (nucleosides). Most importantly,