Abstract In the present study, some naphthalene derivatives have been synthesized by incorporating azetidinyl and thiazolidinyl moieties at its α-or β-positions such as α-(3-chloro- 2-oxo-4-substituted) aryl-1-azetidinyl) naphthalenes 6–10, α-((substituted) aryl-4-oxo-1, 3- thiazolidin-3-yl) naphthalenes 11–15, β-(3-chloro-2-oxo-4-substituted aryl-1-azetidinyl) naphthalenes 21–25, and β-(substituted aryl-4-oxo-1, 3-thiazolidin-3-yl) naphthalenes 26 ...