35. Acyl derivatives of p-aminobenzenesulphonylguanidine

PR Carter, DH Hey, DS Morris

文献索引：Carter; Hey Journal of the Chemical Society, 1948 , p. 147

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摘要

OF the various chemotherapeutic agents of the sulphonamide group, P- aminobenzenesulphonylguanidine (sulphaguanidine) is one of the most effective in the treatment of certain pathogenic infections of the intestinal tract. Divinskii and Vorob'eva (Compt. rend. Acad. Sci. URSS, 1942, 36, 203) observed that many sulphonamides are acetylated in vivo to give the less toxic acetyl derivatives, and showed that p- ...