A series of quinoline coupled 1, 2, 3-triazoles compounds have been synthesized by 'click chemistry'from azidomethyl quinoline with different alkynes. The efficiency and fidelity of the Cu (I)-catalyzed azide–alkyne reaction are substantiated by good yields and exclusive formation of the expected 1, 4-disubstituted triazole product. All the synthesized compounds were screened for anti-tubercular activity against Mycobacterium tuberculosis H37Rv by ...
