Journal of medicinal chemistry

Tumor Inhibitors. XXV. The Synthesis and Evaluation of 9-Nitro-1, 2, 3, 4-tetrahydrophenanthrene-8-carboxylic Acid

SM Kupchan, M Mokotoff

文献索引：Kupchan,S.M.; Mokotoff,M. Journal of Medicinal Chemistry, 1967 , vol. 10, p. 977 - 979

全文：HTML全文

被引用次数: 0

摘要

In the course of a continuing search for tumor iii-hibitors of plant origin, aristolochic acid (I) was characterized as a tumor (; lderiocxrc~ irionia I m)-inhibitory principle from Aristolochiu indica. A subsequent report'desrribed H synthetic qqxwch to aristolochic acid arid related phenanthrene carboxylic:~ cids.~ We report herewith t> he synthesis and evaluntion of an: iristolochic acid arialog without oxygeii ether fuiictioiis: md with a saturated ring, namely 9- ...