Copper-Catalyzed Radical Methylation/C–H Amination/Oxidation Cascade for the Synthesis of Quinazolinones

…, Y Yan, K Xu, J Su, Z Zha, Z Wang

文献索引：Zhang, Jintang; Yu, Chenmin; Wang, Sujing; Wan, Changfeng; Wang, Zhiyong Chemical Communications, 2010 , vol. 46, # 29 p. 5244 - 5246

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被引用次数: 11

摘要

A copper-catalyzed radical methylation/sp3 C–H amination/oxidation reaction for the facile synthesis of quinazolinone was developed. In this cascade reaction, dicumyl peroxide acts not only as a useful oxidant but also as an efficient methyl source. Notably, a methyl radical,