Tetrahedron Letters

An alumina-catalyzed Michael addition of mercaptans to N-anilinomaleimides and its application to the solution-phase parallel synthesis of libraries

S Cheng, DD Comer

文献索引：Cheng, Soan; Comer, Daniel D Tetrahedron Letters, 2002 , vol. 43, # 7 p. 1179 - 1181

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被引用次数: 46

摘要

A novel strategy for the synthesis of 3-sulfanylsubstituted 1-(arylamino)-pyrrolidine-2, 5- dione derivatives via the alumina-catalyzed Michael addition of mercaptans to N- anilinomaleimides is described. The utilization of alumina in the synthesis offers important ...