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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Naphthoquinone Antimalarials. IV-XI. Synthesis1

LF Fieser, E Berliner, FJ Bondhus…

文献索引：Fieser et al. Journal of the American Chemical Society, 1948 , vol. 70, p. 3177

全文：HTML全文

被引用次数: 53

摘要

The synthesis of 3-alkyl or aralkyl derivatives of 2-hydroxy-l, 4-naphthoquinone has been accomplished by condensation of the hydroxyquinone with an aldehyde and hydrogenation of the resulting 3-a-alkenyl derivative, 2 by the action of an allylic or benzyl halide on the hydroxyquinone silver salt to produce 3-derivatives either by direct C-alkylation or by rearrangement of an allylic ether, 3f4 and, in a few special cases, by condensation of the ...

2-羟基-1,4萘醌结构式

2-羟基-1,4萘醌

~%

4-hydroxy-3-(4-phenylphenyl)naphthalene-1,2-dione结构式

4-hydroxy-3-(4-...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

4-hydroxy-3-(4-phenylphenyl)naphthalene-1,2-dione结构式

4-hydroxy-3-(4-...

1,4-萘醌结构式

~%

4-hydroxy-3-(4-phenylphenyl)naphthalene-1,2-dione结构式

4-hydroxy-3-(4-...

环氧乙烷结构式

~%

3-丙基-1-己醇结构式

3-丙基-1-己醇

naphthalene-1,2,4-triol结构式

naphthalene-1,2...

环己烯结构式

~%

帕伐醌结构式

2-羟基-1,4萘醌结构式

2-羟基-1,4萘醌

~%

帕伐醌结构式

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

帕伐醌结构式

1,4-萘醌结构式

~%

帕伐醌结构式

乙醇结构式

1a-cyclohexyl-1a,7a-dihydronaphth[2,3b]oxirene-2,7-dione结构式

1a-cyclohexyl-1...

甲醇钠结构式

~%

2-羟基-1,4萘醌结构式

2-羟基-1,4萘醌

详细

2-羟基-1,4萘醌结构式

2-羟基-1,4萘醌

~%

3-(3-(3-Cyclohexylphenyl)propyl)-2-hydroxynaphthalene-1,4-dione结构式

3-(3-(3-Cyclohe...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

3-(3-(3-Cyclohexylphenyl)propyl)-2-hydroxynaphthalene-1,4-dione结构式

3-(3-(3-Cyclohe...

1,4-萘醌结构式

~%

3-(3-(3-Cyclohexylphenyl)propyl)-2-hydroxynaphthalene-1,4-dione结构式

3-(3-(3-Cyclohe...

乙醇结构式

~%

SL 11039结构式

盐酸结构式

(3,4-dioxonaphthalen-1-yl)cyanamide结构式

(3,4-dioxonapht...

~%

SL 11039结构式

2-isopentyl-naphthalene结构式

2-isopentyl-nap...

~%

1,4-Naphthalenedione,2-(3-methylbutyl)-结构式

1,4-Naphthalene...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

4-hydroxy-3-pentadecyl-naphthalene-1,2-dione结构式

4-hydroxy-3-pen...

1,4-萘醌结构式

~%

4-hydroxy-3-pentadecyl-naphthalene-1,2-dione结构式

4-hydroxy-3-pen...

棕榈酰氯结构式

~%

4-hydroxy-3-pentadecyl-naphthalene-1,2-dione结构式

4-hydroxy-3-pen...

6-氯-6-氧代己酸乙酯(硫辛酸杂质)结构式

6-氯-6-氧代己酸乙酯(硫辛酸杂质)

溴苯结构式

~%

ethyl 6-(4-bromophenyl)-6-oxohexanoate结构式

ethyl 6-(4-brom...

3-(3-三氟甲基苯基)丙酸结构式

3-(3-三氟甲基苯基)丙酸

~%

3-(3-(trifluoromethyl)phenyl)propanamide结构式

3-(3-(trifluoro...

3-(3-(trifluoromethyl)phenyl)propanoyl chloride结构式

3-(3-(trifluoro...

~%

3-(3-(trifluoromethyl)phenyl)propanamide结构式

3-(3-(trifluoro...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

2-甲氧基-1,4-萘并醌结构式

2-甲氧基-1,4-萘并醌

1,4-萘醌结构式

~%

2-甲氧基-1,4-萘并醌结构式

2-甲氧基-1,4-萘并醌

3,3-二苯基丙酸乙酯结构式

3,3-二苯基丙酸乙酯

~%

Benzenebutanoic acid, g-phenyl-结构式

Benzenebutanoic...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

1,4-Naphthalenedione,2-[3-(4-chlorophenyl)propyl]-3-hydroxy-结构式

1,4-Naphthalene...

1,4-萘醌结构式

~%

1,4-Naphthalenedione,2-[3-(4-chlorophenyl)propyl]-3-hydroxy-结构式

1,4-Naphthalene...

2-羟基-1,4萘醌结构式

2-羟基-1,4萘醌

~%

1,4-Naphthalenedione,2-[3-(4-chlorophenyl)propyl]-3-hydroxy-结构式

1,4-Naphthalene...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

4-hydroxy-3-undecylnaphthalene-1,2-dione结构式

4-hydroxy-3-und...

1,4-萘醌结构式

~%

4-hydroxy-3-undecylnaphthalene-1,2-dione结构式

4-hydroxy-3-und...

4-苯基丁酸结构式

~%

4-环己基-1-丁醇结构式

4-环己基-1-丁醇

乙醇结构式

4-环己烷丁酸结构式

4-环己烷丁酸

~%

4-环己基-1-丁醇结构式

4-环己基-1-丁醇

丁二烯结构式

2-苯基-1,4-苯醌结构式

2-苯基-1,4-苯醌

~%

1,4-Naphthalenedione,2-phenyl-结构式

1,4-Naphthalene...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

1,4-Naphthalenedione,2,2'-methylenebis[3- hydroxy-结构式

1,4-Naphthalene...

1,4-萘醌结构式

~%

1,4-Naphthalenedione,2,2'-methylenebis[3- hydroxy-结构式

1,4-Naphthalene...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

1,4-Naphthalenedione,2-(3,7-dimethyloctyl)-3-hydroxy-结构式

1,4-Naphthalene...

1,4-萘醌结构式

~%

1,4-Naphthalenedione,2-(3,7-dimethyloctyl)-3-hydroxy-结构式

1,4-Naphthalene...

2-羟基-1,4萘醌结构式

2-羟基-1,4萘醌

~%

1,4-Naphthalenedione,2-(3,7-dimethyloctyl)-3-hydroxy-结构式

1,4-Naphthalene...

氰氨化钙结构式

~%

(3,4-dioxonaphthalen-1-yl)cyanamide结构式

(3,4-dioxonapht...

1,4-二乙酰氧基萘结构式

1,4-二乙酰氧基萘

~%

4-propan-2-yloxynaphthalen-1-ol结构式

4-propan-2-ylox...

(4-acetyloxy-5,8-dihydronaphthalen-1-yl) acetate结构式

(4-acetyloxy-5,...

~%

4-propan-2-yloxynaphthalen-1-ol结构式

4-propan-2-ylox...

1,4-萘醌结构式

~%

4-propan-2-yloxynaphthalen-1-ol结构式

4-propan-2-ylox...

2-羟基-1,4萘醌结构式

2-羟基-1,4萘醌

异丙醇结构式

~%

2-propan-2-yloxynaphthalene-1,4-dione结构式

2-propan-2-ylox...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

2-propan-2-yloxynaphthalene-1,4-dione结构式

2-propan-2-ylox...

1,4-萘醌结构式

~%

2-propan-2-yloxynaphthalene-1,4-dione结构式

2-propan-2-ylox...

6-(4-chlorophenyl)-6-oxohexanoic acid结构式

6-(4-chlorophen...

~%

6-(4-chlorophenyl)hexanoic acid结构式

6-(4-chlorophen...

2-羟基-1,4萘醌结构式

2-羟基-1,4萘醌

~%

2-morpholin-4-ylnaphthalene-1,4-dione结构式

2-morpholin-4-y...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

2-morpholin-4-ylnaphthalene-1,4-dione结构式

2-morpholin-4-y...

1,4-萘醌结构式

~%

2-morpholin-4-ylnaphthalene-1,4-dione结构式

2-morpholin-4-y...

吗啉结构式

2-甲氧基-1,4-萘并醌结构式

2-甲氧基-1,4-萘并醌

~%

2-morpholin-4-ylnaphthalene-1,4-dione结构式

2-morpholin-4-y...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

1,4-Naphthalenedione, 2-hydroxy-3-(3-(4-phenoxyphenyl)propyl)-结构式

1,4-Naphthalene...

1,4-萘醌结构式

~%

1,4-Naphthalenedione, 2-hydroxy-3-(3-(4-phenoxyphenyl)propyl)-结构式

1,4-Naphthalene...

2-羟基-1,4萘醌结构式

2-羟基-1,4萘醌

~%

1,4-Naphthalenedione, 2-hydroxy-3-(3-(4-phenoxyphenyl)propyl)-结构式

1,4-Naphthalene...

十一烷酰氯结构式

十一烷酰氯

~%

3-decyl-4-hydroxy-naphthalene-1,2-dione结构式

3-decyl-4-hydro...

乙酸酐结构式

~%

(4-acetyloxy-5,8-dihydronaphthalen-1-yl) acetate结构式

(4-acetyloxy-5,...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

4-hydroxy-3-(2-methyloctyl)naphthalene-1,2-dione结构式

4-hydroxy-3-(2-...

1,4-萘醌结构式

~%

4-hydroxy-3-(2-methyloctyl)naphthalene-1,2-dione结构式

4-hydroxy-3-(2-...

2-羟基-1,4萘醌结构式

2-羟基-1,4萘醌

~%

4-hydroxy-3-(2-methyloctyl)naphthalene-1,2-dione结构式

4-hydroxy-3-(2-...

重氮苯磺酸结构式

重氮苯磺酸

邻环己酚结构式

~%

4-氨基-2-环己基苯酚结构式

4-氨基-2-环己基苯酚

未登录结构式

~%

5,9-dimethyldecanoic acid结构式

5,9-dimethyldec...

癸酰氯结构式

~%

4-hydroxy-3-nonylnaphthalene-1,2-dione结构式

4-hydroxy-3-non...

环氧乙烷结构式

~%

3-(三氟甲基)苯乙醇结构式

3-(三氟甲基)苯乙醇

甲醇结构式

~%

2-Naphthalenebutanoicacid, 5,6,7,8-tetrahydro-, methyl ester结构式

2-Naphthalenebu...

2-羟基-1,4萘醌结构式

2-羟基-1,4萘醌

ditridecanoyl peroxide结构式

ditridecanoyl p...

~%

羟基灭螨醌结构式

羟基灭螨醌

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

羟基灭螨醌结构式

羟基灭螨醌

1,4-萘醌结构式

~%

羟基灭螨醌结构式

羟基灭螨醌

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

4-hydroxy-3-(4-methoxyphenyl)naphthalene-1,2-dione结构式

4-hydroxy-3-(4-...

1,4-萘醌结构式

~%

4-hydroxy-3-(4-methoxyphenyl)naphthalene-1,2-dione结构式

4-hydroxy-3-(4-...

2-羟基-1,4萘醌结构式

2-羟基-1,4萘醌

diheptanoyl peroxide结构式

diheptanoyl peroxide

~%

3-hexyl-4-hydroxynaphthalene-1,2-dione结构式

3-hexyl-4-hydro...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

3-hexyl-4-hydroxynaphthalene-1,2-dione结构式

3-hexyl-4-hydro...

1,4-萘醌结构式

~%

3-hexyl-4-hydroxynaphthalene-1,2-dione结构式

3-hexyl-4-hydro...

2-羟基-1,4萘醌结构式

2-羟基-1,4萘醌

二异丁酰基过氧化物结构式

二异丁酰基过氧化物

~%

1,4-Naphthalenedione,2-hydroxy-3-(1-methylethyl)-结构式

1,4-Naphthalene...

1,2,4-Naphthalenetriol,1,2,4-triacetate结构式

1,2,4-Naphthale...

~%

1,4-Naphthalenedione,2-hydroxy-3-(1-methylethyl)-结构式

1,4-Naphthalene...

1,4-萘醌结构式

~%

1,4-Naphthalenedione,2-hydroxy-3-(1-methylethyl)-结构式

1,4-Naphthalene...

(4-acetyloxy-5,8-dihydronaphthalen-1-yl) acetate结构式

(4-acetyloxy-5,...

~%

1,4-二乙酰氧基萘结构式

1,4-二乙酰氧基萘

己酰氯结构式

~%

4-hydroxy-3-pentylnaphthalene-1,2-dione结构式

4-hydroxy-3-pen...