7'-substituted benzothiazolothio-and pyridinothiazolothio-purines as potent heat shock protein 90 inhibitors

L Zhang, J Fan, K Vu, K Hong…

文献索引：Fujii, Tozo; Saito, Tohru; Fujisawa, Tetsunori Heterocycles, 1988 , vol. 27, # 5 p. 1163 - 1166

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被引用次数: 84

摘要

... Volume: Page: ... To prepare the thiazolopyridine-2-thiols 77 and 78 (Scheme 7), the 5-Cl or 5-Br was introduced by halogenation 26 of 3 ... Subsequently, the 4-OH group was converted to chlorine by treating with POCl 3 , 27 and the nitro group was reduced to an ...