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Journal of the American Chemical Society

Piperidine Derivatives. XV. The Preparation of 1-Benzoyl-3-carbethoxy-4-piperidone. A Synthesis of Guvacine

SM McElvain, G Stork

文献索引:McElvain; Stork Journal of the American Chemical Society, 1946 , vol. 68, p. 1049,1052

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被引用次数: 34

摘要

Summary The synthesis of twenty-seven new metanilamides, three new orthanilamides, and seventeen variously substituted 2-phenylsulfonamidopyrimidines has been described. 2. The antimalarial activities of these compounds in avian malaria have been reported and discussed with respect to their structure. 3. Among the metanilamides studied, a majority of the N1-heterocyclic compounds showed antimalarial activity; other types of metanilamides ...