Catalytic Self??Screening of Cholinesterase Substrates from a Dynamic Combinatorial Thioester Library

R Larsson, Z Pei, O Ramström

文献索引：Larsson, Rikard; Pei, Zhichao; Ramstroem, Olof Angewandte Chemie - International Edition, 2004 , vol. 43, # 28 p. 3716 - 3718

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被引用次数: 83

摘要

Dynamic combinatorial chemistry (DCC) has proven to be a useful tool in the rapid identification of ligands and inhibitors for receptors and enzymes, as well as receptors for certain ligands.[1–6] The technique relies on reversible interconnections between building elements, assembled into discrete entities of interacting species, which constitute libraries of dynamically interchanging species. Different formats of the technique have been ...