4-Amino-2-(aryl)-butylbenzamides and Their conformationally constrained analogues. Potent antagonists of the human neurokinin-2 (NK 2) receptor

AR MacKenzie, AP Marchington, DS Middleton…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 13 p. 2211 - 2215

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被引用次数: 11

摘要

... Bioorganic & Medicinal Chemistry Letters. ... 6 Our initial studies in this area, however, were hampered by the lack of attractive chemical leads both as mechanistic tools and as starting points for a medicinal chemistry programme. ...