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Tetrahedron

The synthesis of morusin as a potent antitumor agent

TH Tseng, SK Chuang, CC Hu, CF Chang, YC Huang…

文献索引:Tseng, Tsui-Hwa; Chuang, Shien-Kai; Hu, Chao-Chin; Chang, Chia-Fu; Huang, Yu-Chao; Lin, Cheng-Wei; Lee, Yean-Jang Tetrahedron, 2010 , vol. 66, # 6 p. 1335 - 1340

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被引用次数: 29

摘要

Morusin, which can be isolated from Chinese herbal medicine, is achieved in which the longest linear sequence is only 13 steps in 12% overall yield from commercially available phloroglucinol. In addition, the metal/EtSH reagents for regioselective demethylation of polymethylated morusin were described. Consequently, this strategy provided a concise route to synthesize the morusin analogues as well. Further biological studies of morusin, it ...