Organic letters

Synthesis of Coumarins via Pd-Catalyzed Oxidative Cyclocarbonylation of 2-Vinylphenols

J Ferguson, F Zeng, H Alper

文献索引：Ferguson, Jamie; Zeng, Fanlong; Alper, Howard Organic Letters, 2012 , vol. 14, # 21 p. 5602 - 5605,4

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被引用次数: 2

摘要

Palladium-catalyzed oxidative cyclocarbonylation of 2-vinylphenols constitutes a simple, direct method for the synthesis of coumarins. The reaction conditions, employing low pressures of CO, and air or 1, 4-benzoquinone as the oxidant, are attractive in terms of environmental considerations and operational simplicity. Coumarins with a variety of functional groups were prepared in yields up to 85%.