Synthesis and free radical scavenging activity of some new spiropyranocoumarins

…, IK Kostakis, P Marakos, N Pouli, I Andreadou

文献索引：Panteleon, Vassiliki; Kostakis, Ioannis K.; Marakos, Panagiotis; Pouli, Nicole; Andreadou, Ioanna Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 21 p. 5781 - 5784

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被引用次数: 28

摘要

A series of novel spiro-substituted 4-hydroxypyranocoumarins and their corresponding dihydropyrano cis-diols has been synthesized. Among them the spiroadamantylpyranocoumarin and the diols can interact with the stable free radical 1, 1- diphenyl-2-picrylhydrazyl and scavenge superoxide anions generated in the xanthine– xanthine oxidase system.