Discovery of a 5 H-Benzo [4, 5] cyclohepta [1, 2-b] pyridin-5-one (MK-2461) Inhibitor of c-Met Kinase for the Treatment of Cancer

JD Katz, JP Jewell, DJ Guerin, J Lim…

文献索引：Journal of Medicinal Chemistry, , vol. 54, # 12 p. 4092 - 4108

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被引用次数: 33

摘要

... Journal of Medicinal Chemistry. ... Departments of Chemistry, ‡ Oncology, § In Vitro Pharmacology, ∥ Structural Chemistry, ⊥ In Vivo Pharmacology, # Drug Metabolism and Pharmacokinetics, and ?? Basic Pharmaceutical Sciences, Merck Research Laboratories, 33 Avenue ...