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Application of a novel design paradigm to generate general nonpeptide combinatorial scaffolds mimicking beta turns: synthesis of ligands for somatostatin receptors

D Chianelli, YC Kim, D Lvovskiy, TR Webb

文献索引:Bioorganic and Medicinal Chemistry, , vol. 11, # 23 p. 5059 - 5068

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被引用次数: 26

摘要

... Bioorganic & Medicinal Chemistry. ... 1 The development of nonpeptide agonists at peptide receptors has represented a particular challenge in medicinal chemistry. ... for the design of scaffolds, based on fundamental principles, which would be useful to medicinal and combinatorial ...