Involvement of a novel mouse hepatic microsomal esterase, ES46. 5K, in the hydrolysis of phthalate esters.

…, T Matsunaga, I YAMAMOTO, H YOSHIMURA

文献索引：Kayano, Yuichiro; Watanabe, Kazuhito; Matsunaga, Tamihide; Yamamoto, Ikuo; Yoshimura, Hidetoshi Biological and Pharmaceutical Bulletin, 1997 , vol. 20, # 7 p. 749 - 751

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被引用次数: 6

摘要

ES46. 5K, a novel esterase from mouse hepatic microsomes (Watanabe K., et al., Biochem. Mol. Biol. Int., 31, 25-30 (1993)), catalyzed hydrolysis of phthalate esters. ES46. 5K and mouse hepatic microsomes hydrolyzed diethyl-, dibutyl-, diisobutyl-, dioctyl-and diethylhexyl phthalates, whereas dicyclohexyl-and diphenyl phthalates having ring structure were not hydrolyzed by the enzymes. V max (μmol/min/mg protein)/K m (μM) ratios of ES46. 5K for ...