Synthesis

Synthesis of PNA monomers and dimers by Ugi four-component reaction

P Xu, T Zhang, W Wang, X Zou, X Zhang, Y Fu

文献索引：Xu, Ping; Zhang, Ting; Wang, Wenhao; Zou, Xiaomin; Zhang, Xin; Fu, Yiqiu Synthesis, 2003 , # 8 p. 1171 - 1176

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被引用次数: 21

摘要

Abstract Peptide nucleic acids (PNA) have received great attention as tools in molecular biology and biotechnology, diagnostic agents, and potential antisense drugs. Many derivatives and analogues of PNA were designed and prepared to improve their physico- chemical and biological properties. In most cases, PNA oligomers were synthesized by peptide synthesis from N-protected monomers. In this work, a new method to obtain PNA ...