Solvolysis kinetics and mechanism of 3-methyl-1, 3-thiazolidine-2, 4-dione

…, V Štěrba, H Zahradníčková

文献索引：Machacek, Vladimir; Sterba, Vojeslav; Zahradnickova, Helena Collection of Czechoslovak Chemical Communications, 1981 , vol. 46, # 12 p. 3097 - 3103

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被引用次数: 6

摘要

Abstract The hydrolysis kinetics of 3-methyl-1, 3-thiazolidine-2, 4-dione have been studied in aqueous buffers and dilute NaOH solutions. The reaction proceeds via two base-catalyzed steps having different rates. In sodium methoxide solutions 3-methyl-1, 3-thiazolidine-2, 4- dione undergoes one-step methanolysis giving methyl thioglycolate anion as the final product. The rate-limiting step consists in decomposition of the anion CH 3 NCOSCH 2 ...