The Journal of Organic Chemistry

Reagent for the. alpha.,. beta. reduction of conjugated nitriles

JA Profitt, DS Watt, EJ Corey

文献索引：Profitt,J.A. et al. Journal of Organic Chemistry, 1975 , vol. 40, # 1 p. 127 - 128

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被引用次数: 106

摘要

The reduction of a,@-unsaturated nitriles 1 to saturated nitriles 2 often proceeds with concomitant reduction of the nitrile moiety, l decyanation, 2 hydrodimeri~ ation,~ and polymerization. 4 Those procedures reported to afford predominantly the nitrile 2 suffer from poor yields5 and limit-ed6 or uncertain7 scope. We now wish, to report a general procedure for effecting the transformation 1-+ 2 in high yield. x: N x;;-R2 Ri Ri