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Synthesis of 2-substituted benzothiazoles containing amino acid, imino or heteroaryl moieties with anticipated fungicidal activity

GAM Nawwar, NA Shafik

文献索引:Nawwar, Galal A. M.; Shafik, Nancy A. Collection of Czechoslovak Chemical Communications, 1995 , vol. 60, # 12 p. 2200 - 2208

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被引用次数: 10

摘要

The chemistry of benzoazoles is of continuous interest for their various biological acti- vities, the most interesting being the antifungal one1,2. Following our laboratory policy directed to the searching of new agrochemicals and in continuation to our previous work3,4, the present paper deals with the synthesis of 2-substituted benzothiazoles with anticipated biological activity. Cyanoacetic acid and 2-aminothiophenol (I) in one-pot reaction gave benzothiazol-2- ylacetic acid (II) ...