The chromeno-imidazo [1, 2-a] pyridine scaffold was generated in an one pot condensation/ cyclization reaction involving a salicylaldehyde and 1-(cyanomethyl) pyridinium chloride, in aqueous sodium carbonate solution. These novel compounds were isolated in 47–71% yield. The reaction pathway was followed by 1H NMR spectroscopy allowing a clear understanding of the side reactions involved in the process. Different mono-substituted ...
