Synthesis and antimicrobial activity of N 1-benzyl or N 1-benzyloxy-1, 6-dihydro-1, 3, 5-triazine-2, 4-diamines

…, ST Tan, CL Khoo, HM Sim, LW Chan, WK Chui

文献索引：Ma, Xiang; Tan, Soo-Tong; Khoo, Chai-Ling; Sim, Hong-May; Chan, Lai-Wah; Chui, Wai-Keung Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5428 - 5431

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被引用次数: 9

摘要

The emergence and spread of multidrug-resistant strains of Staphylococcus aureus and Mycobacterium tuberculosis are generating a threat to public health worldwide. In the current study, a series of N1-benzyl and N1-benzyloxy-1, 6-dihydro-1, 3, 5-triazine-2, 4- diamine derivatives were synthesized and investigated for their antimicrobial activity against S. aureus, and Mycobacterium smegmatis which is taxonomically related to M. ...