Tetrahedron Letters

Stereoselective synthesis of withafein A and 27-deoxywithaferin A 1

M Hirayama, K Gamoh, N Ikekawa

文献索引：Hirayama; Gamoh; Ikekawa Tetrahedron Letters, 1982 , vol. 23, # 45 p. 4725 - 4728

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被引用次数: 27

摘要

Abstract The first stereoselective synthesis of withaferin A and 27-deoxywithaferin A was described. The key steps in the synthesis involve introduction of the desired substituent at C 25 and steroselective construction of the A: B rings by a facile allyl sulfoxide—sulfenate