A novel series of parenteral cephalosporins exhibiting potent activities against Pseudomonas aeruginosa and other Gram-negative pathogens: Synthesis and …

K Yamawaki, T Nomura, T Yasukata, K Uotani…

文献索引：Yamawaki, Kenji; Nomura, Takashi; Yasukata, Tatsuro; Uotani, Koichi; Miwa, Hideaki; Takeda, Kei; Nishitani, Yasuhiro Bioorganic and Medicinal Chemistry, 2007 , vol. 15, # 21 p. 6716 - 6732

全文：HTML全文

被引用次数: 11

摘要

A series of 7β-[2-(2-aminothiazol-4-yl)-2-(Z)-(carboxymethoxyimino) acetamido] cephalosporins bearing a 1-(substituted)-1H-pyrrolo [3, 2-b] pyridinium group at C-3′ position was synthesized and their in vitro antibacterial activities against Pseudomonas aeruginosa and other Gram-negative pathogens were evaluated. Among the cephalosporins prepared, 7β-[2-(2-amino-5-chlorothiazol-4yl)-2 (Z)-((S)-1- ...