Thiazole analog as stearoyl-CoA desaturase 1 inhibitor

…, L Belair, J Guay, R Murgasva, W Sturkenboom…

文献索引：Li, Chun Sing; Belair, Liette; Guay, Jocelyne; Murgasva, Renata; Sturkenboom, Wayne; Ramtohul, Yeeman K.; Zhang, Lei; Huang, Zheng Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 17 p. 5214 - 5217

全文：HTML全文

被引用次数: 35

摘要

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... SCD1 inhibition may represent a novel treatment for obesity, type-2 diabetes and related metabolic disorders. A prototype thiazole amide analog 13 (MF-152) was identified as an excellent tool in the study of SCD biology in animals. ... A prototype thiazole amide analog 13 (MF-152) ...