Tetrahedron Letters

A mild oxidizing reagent for alcohols and 1, 2-diols: o-iodoxybenzoic acid (IBX) in DMSO

M Frigerio, M Santagostino

文献索引：Frigerio, Marco; Santagostino, Marco Tetrahedron Letters, 1994 , vol. 35, # 43 p. 8019 - 8022

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被引用次数: 562

摘要

Abstract o-Iodoxybenzoic acid (IBX) smoothly oxidizes primary and secondary alcohols to aldehydes and ketones, respectively. 1, 2-Diols are converted to α-ketols or α-diketones without any oxidative cleavage of the glycol C C bond. IBX oxidations are easily conducted in DMSO solution at room temperature, with yields ranging from good to quantitative.