Directed synthesis and immunoactive properties of (2-hydroxyethyl) ammonium salts of 1-R-indol-3-ylsulfanyl (sulfonyl) alkanecarboxylic acids

AN Mirskova, GG Levkovskaya, OP Kolesnikova…

文献索引：Mirskova; Levkovskaya; Kolesnikova; Perminova; Rudyakova; Adamovich Russian Chemical Bulletin, 2010 , vol. 59, # 12 p. 2236 - 2246

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被引用次数: 12

摘要

Abstract A general method for the synthesis of 1-alkyl (allyl)(benzyl)-substituted (indol-3-yl)- sulfanylalkanecarboxylic acids and hexane-1, 6-diyl (1, 4-phenylenemethylene) bisindol-3- ylsulfanylalkanecarboxylic acids from the corresponding N-substituted indoles and bisindoles, thiourea, iodine, and halogencarboxylic acids was developed. The oxidation of substituted (indol-3-yl) sulfanylalkanecarboxylic acids for the first time afforded their ...