Estrogen receptor-β potency-selective ligands: structure-activity relationship studies of diarylpropionitriles and their acetylene and polar analogues

MJ Meyers, J Sun, KE Carlson…

文献索引：Hauser, Frank M.; Ellenberger, Suzanne R. Synthesis, 1987 , # 8 p. 723 - 724

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被引用次数: 592

摘要

... Chemical Synthesis. ... To synthesize the diarylpropionitriles (16a−h), we prepared a-cyanostilbenes 14a−h by the condensation of arylaldehydes and arylacetonitriles 21 ... by the method of Davis and Ward, 27 as shown in Scheme 6. Condensation of p- and m-anisaldehydes with p ...