Medicinal Chemistry Research

Synthesis, antiproliferation, and docking studies of N-phenyl-lipoamide and 8-mercapto-N-phenyloctanamide derivatives: effects of C6 position thiol moiety

SJ Zhang, WX Hu

文献索引：Zhang, Shi-Jie; Hu, Wei-Xiao Medicinal Chemistry Research, 2012 , vol. 21, # 10 p. 3312 - 3320

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被引用次数: 1

摘要

Abstract Some N-phenyl lipoamide and 8-mercapto-N-phenyloctanamide derivatives were synthesized and their in vitro antiproliferative activity was evaluated. The experimental results indicated that 8-mercapto-N-phenyloctanamides might be good histone deacetylase