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Archiv der Pharmazie

Properties and Reactions of Substituted 1, 2??Thiazetidine 1, 1??Dioxides: Alkylation and Acylation of 3??Haloalkyl β??Sultams and Synthesis of Bicyclic β??Sultams

P Schwenkkraus, HH Otto

文献索引:Schwenkkraus; Otto Archiv der Pharmazie, 1990 , vol. 323, # 2 p. 93 - 97

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被引用次数: 10

摘要

Abstract Alkylation of the 3-chloroethyl substituted β-sultam 1 with bromoacetates yields the N-and 3-substituted β-sultams 2; exchange of halogens affords esters 3. Reactions of 1 or of the analogues 8 with isocyanates make the carbamoyl derivatives 5, 6, and 9 available.