Development of selective colorimetric probes for hydrogen sulfide based on nucleophilic aromatic substitution

…, TF Pearce, RJ Hansen, LN Zakharov…

文献索引：Montoya, Leticia A.; Pearce, Taylor F.; Hansen, Ryan J.; Zakharov, Lev N.; Pluth, Michael D. Journal of Organic Chemistry, 2013 , vol. 78, # 13 p. 6550 - 6557

全文：HTML全文

被引用次数: 62

摘要

Hydrogen sulfide is an important biological signaling molecule and an important environmental target for detection. A major challenge in developing H2S detection methods is separating the often similar reactivity of thiols and other nucleophiles from H2S. To address this need, the nucleophilic aromatic substitution (SNAr) reaction of H2S with electron-poor aromatic electrophiles was developed as a strategy to separate H2S and ...