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Total synthesis and biological evaluation of pacidamycin D and its 3′-hydroxy analogue

K Okamoto, M Sakagami, F Feng…

文献索引:Hardy, Christopher R.; Parrick, John Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 506 - 511

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被引用次数: 14

摘要

... The Journal of Organic ... obtained as the major product (entries 3–6). The reaction at the lower temperature improved not only the total chemical yield (87 ... the steric repulsion between the iodo group and the substituents at the C-3′ position (the hydrogen atom and the R group) is ...